Intermittent scanning CGM with low glucose alarm reduces hypoglycemia in type 1 diabetes

The researchers reported that the change to intermittent scanning steady glucose screens with low glucose alarms lowered the frequency of hypoglycemia in middle-aged adults with sort 1 diabetes..

“Just one potential research by Boscari et al confirmed a discount in hypoglycemia episodes after switching from the alarmed Free Model Libre 1 to the Free Model Libre 2.” Philippe OriotMD, He and colleagues wrote from the division of diabetology and endocrinology on the Mouscron Hospital Heart in Belgium. “Right now, there are not any real-life research of the efficacy of the continual alarm FreeStyle Libre 2 in lowering hypoglycemia in comparison with the FreeStyle Libre 1.”

This single-center observational research, revealed within the journal Journal of Diabetes and its IssuesTogether with 108 adults (imply age, 58.2 years; 57.4% male) with type 1 diabetes People who worry hypoglycemia, should not vulnerable to hypoglycemia consciousness, and/or expertise extreme hypoglycemia whereas utilizing intermittent scan CGM FreeStyle Libre 1 (Abbott). Individuals had been switched to an intermittent scan CGM FreeStyle Libre 2 (Abbott) with individually programmable low glucose alarms.

The first end result was the proportion adjustments in time under the ranges under 70 mg/dL and under 54 mg/dL after 12 weeks within the FreeStyle Libre 2 in comparison with the FreeStyle Libre 1. 70 mg/dL to 180 mg/dL vary, share of time above 180 mg/dL vary, imply interstitial glucose, indicator of glycemic administration, interstitial glucose coefficient of variation, HbA1c, and day by day sensor scans.

The researchers noticed that 37% of people with a Clarke hypoglycemia consciousness rating of 4 or larger and 17.5% of people had a historical past of extreme hypoglycemia. Total, the median low glucose alarm threshold was 70 mg/dL.

The proportion of time under the vary under 70 mg/dL decreased from 4.5% within the first 12 weeks on the FreeStyle Libre 2 to 2.3% within the final 12 weeks within the FreeStyle Libre 1 (P < .001). The proportion of time under the vary under 54 mg/dL decreased from 1.4% within the FreeStyle Libre 2 to 0.3% within the FreeStyle Libre 1 (P < .001). Additionally, the proportion of time ranges from 70 mg/dL to 180 mg/dL (51.5% vs. 52.9%; P = .13) and the proportion of time above the vary above 180 mg/dL (44.7% vs 43.8%); P = .5) was not statistically vital between FreeStyle Libre 2 and FreeStyle Libre 1. Interstitial glucose coefficient of variation decreased from 39.4% to 37.9% with FreeStyle Libre 1 (P < .001).

A discount within the incidence of hypoglycemia under 70 mg/dL and under 54 mg/dL has been noticed in individuals in danger for hypoglycemia (P < .0001). Additionally they reported excessive satisfaction with the hypoglycemia alarms, and all people selected to proceed utilizing the person alarms past the research interval.

“These people may expertise fast identification and/or appropriate treatment of hypoglycemia”the researchers wrote. “Subsequently, the FreeStyle Libre 2 with hypoglycemic alarm needs to be helpful for lowering the morbidity and mortality related to hypoglycemia in adults with insulin-treated diabetes.”